Reference

Guide | Reference

109  Medication and Iatrogenic Psychiatric Syndromes

Purpose. Identify medication-induced symptoms before labeling primary disorders. Reduce harm from iatrogenic effects and misdiagnosis.

109.1 Hallmark Signs

• Temporal link to medication start, stop, or dose change.
• New-onset agitation, insomnia, mood elevation, or psychosis.
• Sedation, cognitive slowing, or emotional blunting after medication changes.

109.2 High-Risk Contexts

• Polypharmacy, drug interactions, medically complex patients.
• Steroids, stimulants, sedatives, anticholinergics, and certain antibiotics.

109.3 Minimum Workup (by setting)

• Medication reconciliation with timeline. [E0/U2]
• Review recent changes, adherence, and OTC/supplement use. [E0/U2]

WarningRed flags

• Acute mania/psychosis after medication changes. [E0/U3]
• New neurologic signs or severe autonomic effects. [E0/U3]

Documentation Output. “Medication-induced contribution suspected/probable/confirmed.” Medication timeline and rationale noted.